Became a manufacturer of active pharmaceutical ingredients through the synthesis of pharmaceutical intermediates.

1981Showa 56Received a Technology Improvement Project Research Grant from the Ministry of International Trade and Industry (now the Ministry of Economy, Trade and Industry) for research into the synthesis of cystine and cysteine
1983Showa 58Obtained a patent for the manufacturing method of DL-cysteine ​​or cystine
1985Showa 60Successfully achieved optical resolution of synthetic cystine
1986Showa 61Received a Technology Improvement Project Research Grant from the Ministry of International Trade and Industry (now the Ministry of Economy, Trade and Industry) for research into the optical resolution of DL-cysteine.
Opened a carbocisteine ​​production line.
Received a license to manufacture carbocisteine ​​from the Ministry of Health and Welfare (now the Ministry of Health, Labour and Welfare).
1986年 カルボシステイン生産ラインを開設
1987Showa 62Acetylcysteine ​​received US-DMF approval and underwent the first FDA inspection
1987年 アセチルシステインのUS-DMF承認、第1回FDA査察
1988Showa 63Multi-production line launched.
1988年 マルチ生産ラインを開設
1989Heisei 1Joint research on the synthesis of L-cystine and L-cysteine started with the University of Tsukuba.
1990Heisei 2Established intermediate manufacturing facilities
1992Heisei 4Established the Production Technology Center (within Ashikaga Plant)
1997Heisei 9Nichiri Yakuhin Co., Ltd. established (planning and sales of health foods)
1998Heisei 10Nichiri Kagaku Co., Ltd. established, taking over the reagent business from Nippon Rika Co., Ltd. (Capital: 10 million yen, 100% owned by Nippon Rika Co., Ltd.)
Operations at Tokyo Plant ceased, and manufacturing functions were consolidated at Ashikaga Plant.
1999Heisei 11Head office relocated to its current address
1999年 本社を現住所へ移転