|1939||Company established with the name “Yamamaru Seiyaku.”|
|1944||Company established with the name “Yamamaru Seiyaku.”|
|1950||Succeeded in extracting and separating cystine from natural proteins.|
|1953||Began mass production of Cystine.
L-Cystine used as additive in dry milk for infants.
|1962||Began construction of main plant in Ashikaga City, Tochigi Prefecture.|
|1971||Ministry of Health and Welfare approved L-Cysteine as an additive for perm solutions.|
|1983||Obtained manufacturing patents for DL-Cysteine and Cystine.|
|1985||Received the Clean Japan Center’s Chairman’s Award for contributing to the reuse of resources.
Succeeded at optically resolving synthetic cystine.
|1987||Underwent first GMP inspection of US FDA.|
|1999||Completed new head office building.|
|2004||Obtained ISO 14001 certification.|
|2005||Underwent first GMP inspection of German regional authorities.|
|2009||Underwent second GMP inspection of German regional authorities.|
|2011||Underwent first GMP inspection of Korean FDA.|
|2018||Underwent eighth GMP inspection of US FDA.|